Christina Megli

Toxoplasma gondii infection misdirects placental trophoblast lineage specification

This study shows that Toxoplasma gondii infection redirects placental trophoblast lineage specification, promoting infection-permissive cells over infection-resistant ones.

Excessive immune responses in preterm placental villi compromise trophoblast health

The paper examines immune cell composition and function in placental villi, finding that excessive T cells and cytokines in preterm cases impair trophoblast health.

Oropouche virus infects human placenta explants and trophoblast organoids

This study shows Oropouche virus infects human placenta tissues and trophoblast organoids, potentially causing adverse pregnancy outcomes through vertical transmission.

Vaccine strains of Rift Valley fever virus exhibit attenuation at the maternal-fetal placental interface

This study shows that vaccine strains of Rift Valley fever virus replicate less in placental tissues compared to wild-type strains, suggesting attenuation at the maternal-fetal interface.

Scoping Review of Maternal Monocytes and the Syncytiotrophoblast: Bi-Directional Communication in the Intervillous Space

This review examines maternal monocyte-trophoblast interactions in the intervillous space, identifying four categories of interaction and highlighting their roles in maternal disease.