Mechanistic insights into the allosteric regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis.
Giacomo Carloni, Quentin Gaday, Julienne Petit, Mariano Martínez, Daniela Megrian, Adrià Sogues, Mathilde Ben Assaya, Marcell Kakonyi, Ahmed Haouz, Pedro M. Alzari, Anne Marie Wehenkel
This study investigates the regulatory mechanism of RipA, a cell wall hydrolase in Mtb, through structural and functional analysis of the SteAB system.
bioRxiv · Jun 28, 2025 · PreprintMicrobiology