Adrià Sogues

Nuclear activities and interactome of the NS5 protein of Tick-Borne Encephalitis Virus

This study identifies the nuclear localization and interactome of TBEV NS5 protein, revealing its role in modulating viral replication through interactions with nuclear factors.

Assessing Corynebacterium glutamicum as a surrogate of Mycobacterium tuberculosis for DNA gyrase inhibitor design.

This paper validates Corynebacterium glutamicum as a non-pathogenic surrogate for Mycobacterium tuberculosis to study DNA gyrase and discover new inhibitors.

From fibril to framework: P. abyssi AbpX illuminates a calcium-responsive family of microbial biomatrix proteins that form thermostable hydrogels

This paper investigates AbpX, a microbial biomatrix protein that forms thermostable hydrogels through calcium ion-dependent self-assembly and provides an atomic model of its fibril lattice.

Functional dissection of Wag31 domains for septal recruitment and polar distribution during the cell cycle

This study identifies domains of Wag31 essential for septal recruitment and polar distribution during the cell cycle in Corynebacterium glutamicum.

Cryo-EM structure and polar assembly of the PS2 S-layer of Corynebacterium glutamicum

The paper determines the atomic structure of the PS2 S-layer from Corynebacterium glutamicum using cryo-EM and shows its polar assembly mechanism and phylogenetic distribution.

Mechanistic insights into the allosteric regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis.

This study investigates the regulatory mechanism of RipA, a cell wall hydrolase in Mtb, through structural and functional analysis of the SteAB system.

Cryo-EM analysis of the Bacillus thuringiensis extrasporal matrix identifies F-ENA as a widespread family of endospore appendages across the Firmicutes phylum

The paper identifies F-ENA as a widespread family of endospore appendages in Firmicutes using cryo-EM, revealing their structure and role in spore clustering.