Establishment of a patient-derived adrenocortical carcinoma 3D tumor construct platform for evaluation of therapeutic strategies
Marco A. Rodriguez, Hemamylammal Sivakumar, Liudmila V. Popova, Saeed Derakhshesh, Daniel M. Chopyk, Wayne O. Miles, Priya H. Dedhia, Aleksander Skardal
This paper develops patient-derived ACC tumor constructs to evaluate therapeutic strategies, showing they can test chemotherapies, targeted therapies, and immunotherapies.
bioRxiv · Jan 9, 2026 · PreprintCancer Biology