RSM01, an extended half-life RSV monoclonal antibody with a high barrier to resistance
Jonne Terstappen, Emanuele Gustani‐Buss, Jason S. McLellan, Vicky Lynne Baillie, Louis Bont, Mauricio T. Caballero, Klasina Chappin, Janissa J.A. van Duijn, Robert Jan Lebbink, Isabelle C.E. van Lotringen, Joris J.T. Roggekamp, Anouk Versnel, Marco C. Viveen, Hanneke J.A.A. Van Zoggel, Eveline M. Delemarre, , Natalie I Mazur
This study evaluates the resistance barrier of RSM01, a long-acting RSV monoclonal antibody, showing infrequent and moderate in vitro resistance compared to licensed mAbs.
bioRxiv · Feb 4, 2026 · PreprintMicrobiology