Louis Bont

This study develops a method to differentiate human nasal epithelial cells into airway-like tissues using small molecules, creating disease models for respiratory conditions.

This study evaluates the resistance barrier of RSM01, a long-acting RSV monoclonal antibody, showing infrequent and moderate in vitro resistance compared to licensed mAbs.

This study shows that RSV forms condensates by pre-assembling replication centers within viral particles, explaining infection heterogeneity and enabling efficient replication without requiring pre-existing condensates.

This study examines the RSV response in bronchial epithelial cells from asthma patients and healthy donors, finding impaired antiviral responses in goblet and multiciliated cells in asthma.

The paper identifies three nasal DNA methylation CpG sites that predict childhood allergic disease with high accuracy, validated across Dutch and US Hispanic children.

This study shows that infant RSV immunoprophylaxis with palivizumab alters nasal epithelial DNA methylation at age 6, affecting antiviral defense pathways but not asthma.