Robert Jan Lebbink

Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling

This study develops a method to differentiate human nasal epithelial cells into airway-like tissues using small molecules, creating disease models for respiratory conditions.

RSM01, an extended half-life RSV monoclonal antibody with a high barrier to resistance

This study evaluates the resistance barrier of RSM01, a long-acting RSV monoclonal antibody, showing infrequent and moderate in vitro resistance compared to licensed mAbs.

Rab27-dependent egress of SARS-CoV-2 via secretory amphisomes

This study uses expansion microscopy to show SARS-CoV-2 exits cells via Rab27-dependent amphisome fusion, identifying a potential therapeutic target.