Author
Biomedical Research Institute
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Wannaporn Ittiprasert, Max F. Moescheid, Cristian Chaparro…·Paul J. Brindley
The paper identifies and characterizes genomic safe harbor sites in Schistosoma mansoni to enable consistent transgene activity through CRISPR/Cas-assisted homology-directed repair.
Wannaporn Ittiprasert, Chawalit Chatupheeraphat, Victoria H. Mann…·Paul J. Brindley
This study compares the efficiency of Cas12a and Cas9 for gene knockout and knock-in in Schistosoma mansoni, finding AsCas12a more efficient for knockout but SpCas9 more precise for knock-in.
Wannaporn Ittiprasert, Victoria H. Mann, Shannon E. Karinshak…·Paul J. Brindley
This paper demonstrates CRISPR/Cas9-based genome editing in Schistosoma mansoni, successfully mutating the omega-1 gene and reducing Th2 cytokine responses and granuloma formation.