Author

André Miller

Biomedical Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3

Frequent Co-Authors

Paul J. BrindleyiD· 3 shared Victoria H. ManniD· 3 shared Wannaporn IttiprasertiD· 3 shared Margaret M. Mentink‐Kane· 2 shared Rutchanee RodpaiiD· 2 shared Anastas S. PopratiloffiD· 1 shared Chawalit ChatupheeraphatiD· 1 shared Christoph Gero GreveldingiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersMolecular Biology

Paul J. BrindleyORCID

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Author profile →

3 papers

Recent·Most cited

Targeted insertion and reporter transgene activity at a gene safe harbor of the human blood fluke, Schistosoma mansoni

Wannaporn Ittiprasert, Max F. Moescheid, Cristian Chaparro, Victoria H. Mann, Thomas Quack, Rutchanee Rodpai, André Miller, Prapakorn Wisitpongpun, Watunyoo Buakaew, Margaret M. Mentink‐Kane, Sarah R. Schmid, Anastas S. Popratiloff, Christoph Gero Grevelding, Christoph Grunau, Paul J. Brindley

The paper identifies and characterizes genomic safe harbor sites in Schistosoma mansoni to enable consistent transgene activity through CRISPR/Cas-assisted homology-directed repair.

Cell Reports Methods · Jul 1, 2023Peer-reviewedMolecular Biology

RNA-guided Cas12a and Cas9 knockout and knockin of the omega-1 locus of Schistosoma mansoni

Wannaporn Ittiprasert, Chawalit Chatupheeraphat, Victoria H. Mann, Wenhui Li, André Miller, Taiwo Ogunbayo, Kenny Tran, Yousef N. Alrefaei, Margaret M. Mentink‐Kane, Paul J. Brindley

This study compares the efficiency of Cas12a and Cas9 for gene knockout and knock-in in Schistosoma mansoni, finding AsCas12a more efficient for knockout but SpCas9 more precise for knock-in.

International Journal of Molecular Sciences · Jan 6, 2022Peer-reviewedMolecular Biology

Diminished adherence of Biomphalaria glabrata embryonic cell line to sporocysts of Schistosoma mansoni following programmed knockout of the allograft inflammatory factor

Fernanda Sales Coelho, Rutchanee Rodpai, André Miller, Shannon E. Karinshak, Victoria H. Mann, Omar dos Santos Carvalho, Roberta Lima Caldeira, Marina de Moraes Mourão, Paul J. Brindley, Wannaporn Ittiprasert

This paper uses CRISPR/Cas9 to knockout the BgAIF gene in Bge cells, showing reduced adherence to Schistosoma mansoni sporocysts.

Parasites & Vectors · Oct 13, 2020Peer-reviewedMolecular Biology