Shannon E. Karinshak

This paper identifies and characterizes SmNAGAL, a glycosyl hydrolase in Schistosoma mansoni, showing its role in coordinating parasite movement and egg production, suggesting it as a potential target for new anthelmintic drugs.

The paper shows that CagA+ Helicobacter pylori infection induces epithelial to mesenchymal transition in human cholangiocytes, promoting migration, invasion, and colony formation.

This paper uses CRISPR/Cas9 to knockout the BgAIF gene in Bge cells, showing reduced adherence to Schistosoma mansoni sporocysts.

The paper investigates how liver fluke granulin promotes exosome-mediated crosstalk that alters the cellular microenvironment to support cholangiocarcinoma development.

This paper demonstrates CRISPR/Cas9-based genome editing in Schistosoma mansoni, successfully mutating the omega-1 gene and reducing Th2 cytokine responses and granuloma formation.

This study uses CRISPR/Cas9 to knockout the Ov-grn-1 gene in liver flukes, showing reduced biliary tract pathology in infected hamsters.