Pharmacology & ToxicologyMolecular PharmacologyPeer-reviewed
Screening for novel RyR2 inhibitors by ER Ca2+ monitoring
Mai Takenaka, Masami Kodama, Takashi Murayama…·Nagomi Kurebayashi
This study identifies three RyR2 inhibitors using an ER Ca2+ monitoring assay, showing they suppress arrhythmogenic Ca2+ waves without affecting normal Ca2+ transients.