Inter-cellular mRNA Transfer Alters Human Pluripotent Stem Cell State
Yosuke Yoneyama, Ranran Zhang, Mari Maezawa, Hideki Masaki, Masaki Kimura, Yuqi Cai, Mike Adam, Sreeja Parameswaran, Naoaki Mizuno, Joydeep Bhadury, So Maezawa, Hiroshi Ochiai, Hiromitsu Nakauchi, S. Steven Potter, Matthew T. Weirauch, Takanori Takebe
The paper shows that inter-species mRNA transfer from mouse embryonic stem cells to human pluripotent stem cells reprograms them to a naive-like state through specific transcription factors.
Proceedings of the National Academy of Sciences · Jan 22, 2025Peer-reviewedCell Biology