A bivalent VP2 based vaccine approach reveals co expression driven interference between VP2 antigens impairing BTV neutralizing antibody induction
Luis Jimenez-Cabello, Juana Sanchez-Puig, Ivan Mazuecos-Aragones…·Javier Ortego
This study develops a bivalent vaccine approach using BTV VP2 antigens and finds that co-expression of VP2 proteins interferes with neutralizing antibody induction, while monovalent vaccines provide effective protection.