Cell Size Modulates SBF and Whi5 Chromatin Binding to Regulate the Start of the Budding Yeast Cell Cycle
Huan Zheng, Ana Paulina Gutierrez Alejandre, Masoumeh Shafieidarabi, Matthew P. Swaffer, Ziad W. El‐Hajj, Maria Vera, Jan Marcel Skotheim, Rodrigo Reyes‐Lamothe
The paper shows that cell size affects SBF and Whi5 chromatin binding to regulate the Start transition in budding yeast by altering their copy-number ratio and chromatin affinity.
bioRxiv · Feb 17, 2026 · PreprintCell Biology