Pumilio and Brain tumor regulate the expression of Smaug during the Drosophila maternal-to-zygotic transition
Alexander J Marsolais, Mariana Kekis, Harrison W. Smith, Zhuyi Wang, Chalini Weerasooriya, Timothy R. Hughes, Howard D. Lipshitz, Craig A. Smibert
This study shows that Pumilio and Brain tumor regulate Smaug mRNA degradation during the Drosophila maternal-to-zygotic transition, preventing ectopic Smaug protein expression and ensuring proper mRNA clearance.
Genetics · Sep 29, 2026Peer-reviewedDevelopmental Biology