Assigning Function To Natural Allelic Variation Via Dynamic Modeling Of Gene Network Induction
Magali Richard, Florent Chuffart, Hélène Duplus‐Bottin, Fanny Pouyet, Martin Spichty, Etienne Fulcrand, Marianne Entrevan, Audrey Barthelaix, Michael Springer, Daniel Jost, Gaël Yvert
The paper uses dynamic modeling of gene networks to interpret natural DNA variants by personalizing model parameters based on genotype, revealing how variants affect molecular regulation in yeast.
Molecular Systems Biology · Jan 1, 2018Peer-reviewedSystems Biology