Fanny Pouyet

The paper identifies mutational signatures caused by DNA:RNA hybrids in yeast genomes, revealing a common mechanism of genetic instability through repair pathways.

The paper maps mutation patterns around human transcription start sites, revealing hypermutation and gBGC effects shaping their evolution.

This study examines how meiotic frequency and sexual strategies affect genetic diversity in facultatively sexual species like yeast, showing that low meiotic frequency can reduce genome-wide diversity during selective sweeps.

The paper investigates the evolutionary forces shaping GC-content at gene transcriptional start sites, finding that recombination patterns drive GC-content changes in mammals.

The paper uses dynamic modeling of gene networks to interpret natural DNA variants by personalizing model parameters based on genotype, revealing how variants affect molecular regulation in yeast.