NeurosciencebioRxivPreprint
Increased Activity of Tyrosine Hydroxylase Leads to Elevated Amphetamine Response and Markers of Oxidative Stress in Transgenic Mice
Laura Marie Vecchio, Marie Kristel Bermejo, Amy R. Dunn…·Ali Salahpour
This study shows that increased tyrosine hydroxylase activity in mice leads to higher dopamine levels, amphetamine response, and oxidative stress markers, suggesting a potential mechanism for neurodegeneration in Parkinson's disease.
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