Cell BiologybioRxivPreprint
MYC Dysregulates Mitotic Spindle Function Creating a Dependency on TPX2
Julia Rohrberg, Alexandra Corella, Moufida Taileb…·Andrei Goga
This study shows MYC dysregulates mitotic spindle function, creating a dependency on TPX2, and identifies a synthetic-lethal interaction between MYC and TPX2 in cancers.