A pre-loaded and assembled human Ago2-miRISC orchestrates Shigella-induced vacuolar rupture through the targeting of RhoGDIα
L Schiavolin, Didier Filopon, Mariette Bonnet, Álvaro L. Pérez‐Quintero, Magali Charvin, B Sperandio, Philippe Jean Sansonetti, Guy Tran Van Nhieu, Lionel Navarro
The paper shows that pre-loaded Ago2-miRISC targets RhoGDIα to facilitate Shigella-induced vacuolar rupture.
bioRxiv · Apr 23, 2025 · PreprintMolecular Biology