Author

Didier Filopon

Centre National de la Recherche ScientifiqueORCID 0000-0003-4949-2280Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Lionel NavarroiD· 2 shared Magali CharviniD· 2 shared Álvaro L. Pérez‐QuinteroiD· 1 shared Antoine AlamiD· 1 shared B Sperandio· 1 shared Bérangère LombardiD· 1 shared Carmen BuchrieseriD· 1 shared Christophe RusniokiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Lionel NavarroORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 23, 2025

A pre-loaded and assembled human Ago2-miRISC orchestrates Shigella-induced vacuolar rupture through the targeting of RhoGDIα

L Schiavolin, Didier Filopon, Mariette Bonnet…·Lionel Navarro

The paper shows that pre-loaded Ago2-miRISC targets RhoGDIα to facilitate Shigella-induced vacuolar rupture.

DOI 10.1101/2025.04.23.650266

humanexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintNov 16, 2022

A Legionella pneumophila effector impedes host gene silencing to promote virulence

Justine Toinon, Monica Rolando, Magali Charvin…·Lionel Navarro

This paper shows that the Legionella pneumophila effector LegK1 suppresses RNA silencing by interacting with Argonaute proteins and activating NF-κB signaling, enhancing bacterial virulence.

1 citation

humanexperimental assay

𝕏 PostBluesky