The long isoform of ZAP coordinates multiple enzymes to mediate complete decay of target transcripts
Clément R. Bouton, Grega Gimpelj Domjanič, María José Lista, Rui Pedro Galão, Thomas Courty, Piotr Kwiatkowski, Harry Wilson, Peter W. S. Hill, Hannah E. Mischo, Anob M. Chakrabarti, Mario Poljak, Jernej Ule, Stuart J. D. Neil, Chad M. Swanson
This study identifies how the long ZAP isoform recruits enzymes to degrade viral RNA through a coordinated decay pathway.
Cell Reports · May 1, 2026Peer-reviewedImmunology