Arp2/3-mediated turnover of large clathrin lattices is regulated through the tyrosine kinase ACK
Mark A. Hazelbaker, Dennis J. Michalak, Mitchell T. Butler, Jordan R. Beach, Justin W. Taraska, James E. Bear
The paper identifies ACK as a regulator of LACL turnover by promoting actin branching to resolve arrested clathrin lattices in Arpc2 KO cells.
bioRxiv · Jun 15, 2026 · PreprintCell Biology