Structure-guided vaccination elicits broadly neutralizing antibodies targeting the HIV-1 silent face
Joshua J. Carter, Maria Belen Palacio, Mark E. Berlaga, Okikiola Morenike Olajide, Joseph J. Noh, Yu Erica Lee, Israel Ramos, Michael R. Eso, Jennie L. Phung, Teresia Chen, Sowmya Meka, Mercedes Guadalupe Garay, Michael S. Seaman, Amelia Escolano, Christopher O. Barnes
This study shows that structure-guided vaccination can elicit broadly neutralizing antibodies targeting the HIV-1 silent face, expanding vaccine strategies.
bioRxiv · Oct 2, 2026 · PreprintImmunology