Author

Mark Platt

University of Liverpool

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

Harish PoptaniiD· 2 shared Anca Croitor· 1 shared Antonius PlaggeiD· 1 shared Birger TielemansiD· 1 shared Catia AttanasioiD· 1 shared Ellen Saliën· 1 shared Greetje Vande VeldeiD· 1 shared Kaat Wouters· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Harish PoptaniORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Microcephaly with a disproportionate hippocampal reduction, stem cell loss and neuronal lipid droplet symptoms in Trappc9 KO mice

Sultan Aljuraysi, Mark Platt, Michela Pulix, Harish Poptani, Antonius Plagge

This study investigates Trappc9 KO mice to model human neurodevelopmental disorders, finding microcephaly, hippocampal reduction, stem cell loss, and lipid droplet abnormalities.

bioRxiv · Nov 20, 2023 · PreprintNeuroscience

Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model

Sergi Llambrich, Birger Tielemans, Ellen Saliën, Marta Atzori, Kaat Wouters, Vicky Van Bulck, Mark Platt, Laure Vanherp, Nuria Gallego Fernandez, Laura Grau de la Fuente, Harish Poptani, Lieve Verlinden, Uwe Himmelreich, Anca Croitor, Catia Attanasio, , Greetje Vande Velde

This study evaluates the effects of trisomy and GTE-EGCG treatment on multiple systems in a Down syndrome mouse model, finding that treatment exacerbates trisomic phenotypes rather than rescuing them.

eLife · Oct 6, 2023Peer-reviewedSystems Biology