Uwe Himmelreich

This study investigates the role of oligodendroglia in Wolfram syndrome using mouse models and iPSC-derived cells, finding preserved oligodendroglia function and suggesting alternative targets for treatment.

This study evaluates the effects of trisomy and GTE-EGCG treatment on multiple systems in a Down syndrome mouse model, finding that treatment exacerbates trisomic phenotypes rather than rescuing them.

The paper shows that astrocyte calcium dysfunction leads to early network hyperactivity in Alzheimer's Disease, which can be reversed by restoring calcium signaling.