Author

Sergi Llambrich

KU LeuvenORCID 0000-0001-9980-0208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Greetje Vande VeldeiD· 3 shared Birger TielemansiD· 2 shared Jens Wouters· 2 shared Neus Martínez‐AbadíasiD· 2 shared Alejandro González· 1 shared Anca Croitor· 1 shared Anna Sarlé· 1 shared Anne‐Charlotte JonckheereiD· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersSystems Biology

Greetje Vande VeldeORCID

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3 papers

Recent·Most cited

Systems BiologyeLifePeer-reviewedOct 6, 2023

Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model

Sergi Llambrich, Birger Tielemans, Ellen Saliën…·Greetje Vande Velde

This study evaluates the effects of trisomy and GTE-EGCG treatment on multiple systems in a Down syndrome mouse model, finding that treatment exacerbates trisomic phenotypes rather than rescuing them.

2 citations

mouseexperimental assay

𝕏 PostBluesky

Systems BiologybioRxivPreprintMar 13, 2023

Cardiopulmonary structural, functional and immune-alterations in a Down syndrome mouse model and upon modulation of EGCG

Birger Tielemans, Sergi Llambrich, Laura Seldeslachts…·Greetje Vande Velde

This study examines cardiopulmonary and immunological changes in Ts65Dn mice and evaluates the effects of prenatal GTE-EGCG treatment on these traits.

DOI 10.1101/2023.03.13.532396

mouseexperimental assay

𝕏 PostBluesky

PathologybioRxivPreprintMar 5, 2018

Epigallocatechin-3-Gallate Improves Facial Dysmorphology Associated with Down Syndrome

John M. Starbuck, Sergi Llambrich, Ruben González…·Neus Martínez-Abadías

This study shows EGCG treatment improves facial dysmorphology in DS mouse models and humans but warns against non-prescribed use due to variable outcomes.

DOI 10.1101/276493

mousehuman

𝕏 PostBluesky