Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans
Silvia Maglioni, Alfonso Schiavi, Marlen Melcher, Vanessa Brinkmann, Zhongrui Luo, Anna Laromaine, Nuno Raimundo, Joel N. Meyer, Felix Distelmaier, Natascia Ventura
This study identifies lutein as a potential therapeutic for mitochondrial dysfunction-induced neurodevelopmental defects in C. elegans by restoring neuroligin expression.
Nature Communications · May 12, 2022Peer-reviewedNeuroscience