Virtual screening for small molecule pathway regulators by image profile matching
Mohammad Hossein Rohban, Ashley M. Fuller, Ceryl Tan, Jonathan T. Goldstein, Deepsing Syangtan, Amos Gutnick, Ann Devine, Madhura P. Nijsure, Megan Rigby, Joshua R. Sacher, Steven M. Corsello, Grace B. Peppler, Marta Bogaczynska, Andrew S. Boghossian, Gabrielle E. Ciotti, , Anne Elizabeth Carpenter
The paper identifies small molecule regulators of biological pathways by matching compound effects to known pathway phenotypes in public cell image data.
Cell Systems · Sep 1, 2022Peer-reviewedBioinformatics