Madhura P. Nijsure

This study shows that erythroid precursors in the bone marrow increase local oxygen levels after injury, promoting tissue repair by enhancing angiogenesis and osteogenesis.

This study identifies YAP and TAZ as regulators of periosteal expansion during fracture repair, showing their role in cell proliferation and BMP4 regulation.

This study shows that Cyr61 delivery enhances angiogenesis during bone fracture repair, particularly in fractures with stable fixation, and may have therapeutic potential for poor vascularization.

This paper describes an outreach module designed to engage high school students in orthopaedic research, showing significant learning gains and increased interest in the field.

This study examines the effects of microgravity on iPSC-derived neural organoids using samples from the International Space Station, finding reduced cell proliferation and increased neural maturity in space-cultured organoids.

This study shows YAP and TAZ regulate osteoblast precursor mobilization and angiogenesis during bone development, linking mechanical cues to vascular and bone formation.

The paper identifies small molecule regulators of biological pathways by matching compound effects to known pathway phenotypes in public cell image data.

This study shows YAP and TAZ promote periosteal osteoblast precursor expansion and differentiation to accelerate bone fracture healing.

This study identifies CD49f as a marker to isolate functional human iPSC-derived astrocytes, which can be stimulated to exhibit a neurotoxic phenotype relevant to neurodegenerative diseases.