Author

Grace B. Peppler

Boston UniversityORCID 0000-0001-9723-9656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandra E. MünchiD· 1 shared Alison GoateiD· 1 shared Allison T. HandsiD· 1 shared Amos GutnickiD· 1 shared Andrew S. BoghossianiD· 1 shared Ann DevineiD· 1 shared Anna Podlesny‐DrabiniokiD· 1 shared Anne Elizabeth CarpenteriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alexandra E. MünchORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A rapid, genetically-tractable human iPSC-derived model for studying tissue-resident macrophage biology in Alzheimer's and other diseases

Hyo Lee, Grace B. Peppler, Michael D.E. Sewell, Alexandra E. Münch, Anna Podlesny‐Drabiniok, Jeanne J Kim, Joshua Orrick, Edoardo M. Marcora, Alison Goate

This paper develops a simplified protocol to generate human iPSC-derived macrophage-like cells (iMacs) that exhibit enhanced phagocytic and TREM2-related functions, making them a useful model for studying macrophage biology in Alzheimer's and other diseases.

bioRxiv · Oct 12, 2026 · PreprintNeuroscience

Virtual screening for small molecule pathway regulators by image profile matching

Mohammad Hossein Rohban, Ashley M. Fuller, Ceryl Tan, Jonathan T. Goldstein, Deepsing Syangtan, Amos Gutnick, Ann Devine, Madhura P. Nijsure, Megan Rigby, Joshua R. Sacher, Steven M. Corsello, Grace B. Peppler, Marta Bogaczynska, Andrew S. Boghossian, Gabrielle E. Ciotti, , Anne Elizabeth Carpenter

The paper identifies small molecule regulators of biological pathways by matching compound effects to known pathway phenotypes in public cell image data.

Cell Systems · Sep 1, 2022Peer-reviewedBioinformatics