Author

Marta León

Spanish National Centre for Cardiovascular Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alfonso MoraiD· 1 shared Ayelén Melina SantamansiD· 1 shared Bárbara González‐TerániD· 1 shared David Filgueiras RamaiD· 1 shared Elena Rodríguez· 1 shared Elisa ManieriiD· 1 shared Francisco Miguel CruziD· 1 shared Guadalupe SabioiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alfonso MoraORCID

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1 paper

Recent·Most cited

MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation

Rafael Romero-Becerra, Alfonso Mora, Elisa Manieri, Ivana Nikolić, Ayelén Melina Santamans, Valle Montalvo-Romeral, Francisco Miguel Cruz, Elena Rodríguez, Marta León, Luis Leiva‐Vega, Laura Sanz, Víctor Bondía, David Filgueiras Rama, Luis Jesús Jiménez‐Borreguero, José Jalife, , Guadalupe Sabio

This paper shows that MKK6 deficiency leads to cardiac dysfunction through hyperactivation of the MKK3-p38γ/δ-mTOR pathway, causing hypertrophy and fibrosis, and highlights potential cardiotoxicity of p38 inhibitors.

eLife · Jul 11, 2022Peer-reviewedMolecular Biology