Author
Spanish National Cancer Research CentreORCID 0000-0002-0050-8117Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Edgar Bernardo, Nuria Matesanz, Jorge Luis Torres…·Guadalupe Sabio
The paper investigates the role of MKK3 in adipose tissue during obesity, finding that its activation protects against insulin resistance by enhancing p38-beta signaling.
Sabrina A. Vallone, Ángela Lara Montero, Alba C. Arcones…·Albana Gattelli
This study shows breast tumors sustain growth by manipulating adipocytes into pre-adipocytes through RET signaling, which promotes tumor progression.
Rafael Romero-Becerra, Alfonso Mora, Elisa Manieri…·Guadalupe Sabio
This paper shows that MKK6 deficiency leads to cardiac dysfunction through hyperactivation of the MKK3-p38γ/δ-mTOR pathway, causing hypertrophy and fibrosis, and highlights potential cardiotoxicity of p38 inhibitors.