Radiation-Induced DNA Damage and Repair Effects on 3D Genome Organization
Jacob T. Sanders, Trevor F. Freeman, Yang Xu, Rosela Golloshi, Mary A. Stallard, Ashtyn M Hill, Rebeca San Martin, Adayabalam S. Balajee, Rachel Patton McCord
This study examines how DNA damage and repair affect 3D genome organization using Hi-C in different cell types, finding cell-type-specific changes and TAD boundary strengthening in repair-proficient cells.
Nature Communications · Dec 2, 2020Peer-reviewedGenomics