Author

Masaaki Yokoyama

Institute for Quantitative Biosciences, The University of Tokyo

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Molecular Biology· 1

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Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

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Mariko SasakiiD· 1 shared Takehiko KobayashiiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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1 shared paperMolecular Biology

Mariko SasakiORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintApr 22, 2022

Spt4 drives cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters

Masaaki Yokoyama, Mariko Sasaki, Takehiko Kobayashi

This study identifies Spt4 as a factor that accelerates cellular senescence by promoting non-coding RNA transcription in rDNA clusters, leading to genomic instability and reduced lifespan in yeast.

DOI 10.1101/2022.04.22.488906

yeastDNA methylation

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