Author

Matei David

Ontario Institute for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:long-read sequencing· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Jared T Simpson· 2 shared Lewis Jonathan Dursi· 2 shared Adam D. EwingiD· 1 shared Adriana SalcedoiD· 1 shared Alex Buchanan· 1 shared Amit G. DeshwariD· 1 shared Bryan Lo· 1 shared Catalina V. AngheliD· 1 shared

Activity by Year

2016-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Jared T Simpson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Creating Standards for Evaluating Tumour Subclonal Reconstruction

DREAM SMC-Het Participants, Adriana Salcedo, Maxime Tarabichi, Shadrielle M. G. Espiritu, Amit G. Deshwar, Matei David, Nathan M. Wilson, Stefan C. Dentro, Jeff A. Wintersinger, Lydia Liu, Minjeong Ko, Srinivasan Sivanandan, Hongjiu Zhang, Kaiyi Zhu, Tai-Hsien Ou Yang, , Paul Christopher Boutros

This study develops quantitative metrics and simulated datasets to evaluate subclonal reconstruction methods in tumours.

Nature Biotechnology · Jan 1, 2020Peer-reviewedBioinformatics

Detecting DNA Methylation using the Oxford Nanopore Technologies MinION sequencer

Jared T Simpson, Rachael Workman, Philip C Zuzarte, Matei David, Lewis Jonathan Dursi, Winston Timp

This study quantifies the ability of the MinION sequencer to detect DNA methylation using synthetic DNA and demonstrates reliable prediction of CpG island methylation from single reads.

bioRxiv · Apr 4, 2016Genomics

Nanocall: An Open Source Basecaller for Oxford Nanopore Sequencing Data

Matei David, Lewis Jonathan Dursi, Delia Yao, Paul C Boutros, Jared T Simpson

Nanocall is an open-source basecaller for Oxford Nanopore sequencing data that enables offline analysis and has comparable accuracy to Metrichor's cloud-based solution.

bioRxiv · Mar 28, 2016Bioinformatics