Modifications in the T arm of tRNA globally determine tRNA maturation, function and cellular fitness
Sarah K. Schultz, Christopher D. Katanski, Mateusz Hałucha, Noah Peña, Richard P. Fahlman, Tao Pan, Ute Kothe
This study shows that tRNA modifications in the T arm by TrmA and TruB are essential for tRNA maturation, aminoacylation, and translation, enhancing cellular fitness in E. coli.
Proceedings of the National Academy of Sciences · Jun 18, 2024Peer-reviewedMolecular Biology