Tao Pan

The paper presents a high-resolution multi-omics dataset of surface ocean metagenomes, metatranscriptomes, and tRNA transcripts collected over 48 hours to study microbial responses to environmental change.

The paper studies tRNA gene evolution in Drosophila, finding rapid duplication and loss, sexual dimorphism in expression, and implications for regulatory diversity.

This study shows that tRNA modifications in the T arm by TrmA and TruB are essential for tRNA maturation, aminoacylation, and translation, enhancing cellular fitness in E. coli.

A de novo yeast neochromosome carrying all 275 tRNA genes was built and characterized; it imposes a growth burden, with genome doubling and deletions in haploids possibly reflecting compensation.