Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
Modifications in the T arm of tRNA globally determine tRNA maturation, function and cellular fitness
Sarah K. Schultz, Christopher D. Katanski, Mateusz Hałucha…·Ute Kothe
This study shows that tRNA modifications in the T arm by TrmA and TruB are essential for tRNA maturation, aminoacylation, and translation, enhancing cellular fitness in E. coli.
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