Molecular dependencies and genomic consequences of a global DNA damage tolerance defect
Daniël de Groot, Aldo Spanjaard, Ronak Shah, Maaike Kreft, Ben Morris, Cor Lieftink, Joyce J. I. Catsman, Shirley Ormel, Matilda Ayidah, Bas Pilzecker, Olimpia Alessandra Buoninfante, Paul C.M. van den Berk, Roderick L. Beijersbergen, Heinz Jacobs
The paper investigates the molecular and genomic effects of a global DNA damage tolerance defect, identifying type 3 deletions as a mutational signature of replication stress.
Genome biology · Dec 31, 2024Peer-reviewedMolecular Biology