Chronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity.
Alice P. Sowton, Lorenz M.W. Holzner, Fynn N. Krause, Ruby M. Baxter, Gabriele Mocciaro, Dominika Krzyzanska, Magdalena Minnion, Katie A. O’Brien, Matthew C. Harrop, Paula M. Darwin, Benjamin D. Thackray, Michèle Vacca, Martin Feelisch, Julian Leether Griffin, Andrew J. Murray
This study shows that chronic nitrate supplementation in mice with diet-induced obesity worsens metabolic health and accelerates disease progression, including liver cancer.
American Journal of Physiology-Endocrinology and Metabolism · Dec 9, 2024Peer-reviewedPhysiology