Author

Matthew D. Hurton

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Miler T. LeeiD· 3 shared Alicia McCarthyiD· 1 shared Anne E. CarlsoniD· 1 shared Benjamin BenninkiD· 1 shared Jennifer M. MilleriD· 1 shared Joel C. RosenbaumiD· 1 shared Justin CamachoiD· 1 shared Maitreyi Upadhyay· 1 shared

Activity by Year

2021-2025 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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3 shared papersDevelopmental Biology

Miler T. LeeORCID

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3 papers

Recent·Most cited

H3K4me2 distinguishes a distinct class of enhancers during the maternal-to-zygotic transition

Matthew D. Hurton, Jennifer M. Miller, Miler T. Lee

The paper identifies two subclasses of enhancers during the maternal-to-zygotic transition in zebrafish, distinguished by H3K4me2 presence or absence, and their dependence on NPS factors.

PLoS Biology · Jul 10, 2025Peer-reviewedDevelopmental Biology

Hybridization led to a rewired pluripotency network in the allotetraploid Xenopus laevis

Wesley A. Phelps, Matthew D. Hurton, Taylor N. Ayers, Anne E. Carlson, Joel C. Rosenbaum, Miler T. Lee

The paper shows that hybridization rewired the pluripotency network in Xenopus laevis by divergent activation of subgenomes by OCT4 and SOX2 homologs.

eLife · Oct 3, 2023Peer-reviewedDevelopmental Biology

RNA degradation sculpts the maternal transcriptome during Drosophila oogenesis

Patrick Blatt, Siu Wah Wong-Deyrup, Alicia McCarthy, Shane M. Breznak, Matthew D. Hurton, Maitreyi Upadhyay, Benjamin Bennink, Justin Camacho, Miler T. Lee, Prashanth Rangan

The paper identifies RNA degradation mechanisms during Drosophila oogenesis that sculpt the maternal transcriptome by removing specific RNAs expressed in germline stem cells.

Current Biology · May 13, 2021Peer-reviewedDevelopmental Biology