Miler T. Lee

The paper identifies two subclasses of enhancers during the maternal-to-zygotic transition in zebrafish, distinguished by H3K4me2 presence or absence, and their dependence on NPS factors.

The paper shows that hybridization rewired the pluripotency network in Xenopus laevis by divergent activation of subgenomes by OCT4 and SOX2 homologs.

This study compares the maternal-to-zygotic transition in cnidarian and bilaterian embryos, finding shared regulatory mechanisms and unique features in Hydractinia.

The paper identifies RNA degradation mechanisms during Drosophila oogenesis that sculpt the maternal transcriptome by removing specific RNAs expressed in germline stem cells.

The paper presents an optimized method for rRNA depletion using shorter antisense oligomers and introduces a web tool for oligo design, demonstrating effectiveness in Xenopus laevis and zebrafish.

The paper identifies cis-regulatory elements and trans-factors governing mRNA stability during zebrafish MZT and develops a model to predict mRNA stability.

This study investigates the role of the Paf1 complex in regulating the transcriptome of Saccharomyces cerevisiae, revealing its impact on both coding and noncoding transcripts through transcriptional and post-transcriptional mechanisms.

The paper identifies TMEM16A as the Ca2+-activated Cl- channel responsible for the fast block to polyspermy in Xenopus laevis eggs by showing that its inhibition reduces fertilization-evoked depolarization.