Author

Matthew Dennen

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alejandro De Los AngelesiD· 1 shared Daniela GeorgievaiD· 1 shared Dieter M. EgliiD· 1 shared Gloryn ChiaiD· 1 shared Lisa C. Grossman· 1 shared Michael V. ZuccaroiD· 1 shared Qian DuiD· 1 shared Robert W. Prosser· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperCell Biology

Alejandro De Los AngelesORCID

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1 paper

Recent·Most cited

Low nucleus to cytoplasmic ratio compromises cytokinesis, genome stability and development in haploid embryonic cells

Michael V. Zuccaro, Daniela Georgieva, Shuangyi Xu, Matthew Dennen, Qian Du, Gloryn Chia, Selma Amrane, Lisa C. Grossman, Alejandro De Los Angeles, Robert W. Prosser, Rogerio A. Løbo, Dieter M. Egli

This study shows that a low nucleus-to-cytoplasmic ratio in haploid embryonic cells leads to cytokinesis failure, genome instability, and reduced development.

bioRxiv · Aug 30, 2025 · PreprintCell Biology