Synthesizing Signaling Pathways from Temporal Phosphoproteomic Data
Ali Sinan Köksal, Kirsten Beck, Dylan R. Cronin, Aaron McKenna, Nathan D. Camp, Saurabh Srivastava, Matthew E. MacGilvray, Rastislav Bodík, Alejandro Wolf‐Yadlin, Ernest Fraenkel, Jasmin Fisher, Anthony Gitter
The paper introduces a computational method to identify missing signaling pathway elements from temporal phosphoproteomic data, demonstrating its effectiveness in both human EGF response and yeast osmotic stress response.
Cell Reports · Sep 1, 2018Peer-reviewedBioinformatics