Structural and Spectroscopic Basis for Catalysis by a Class C Radical S-adenosylmethionine Methylase Involved in Nosiheptide/Nocathiacin Biosynthesis
Bo Wang, Hayley L. Knox, Nicholas J. York, Matthew I. Radle, Alexey Silakov, Squire J. Booker
This paper reports the structural and spectroscopic analysis of a class C radical SAM methylase involved in Nosiheptide biosynthesis, revealing key catalytic residues and radical mechanisms.
Journal of the American Chemical Society · May 27, 2026Peer-reviewedBiochemistry