Author

Nicholas J. York

Pennsylvania State UniversityORCID 0000-0001-7054-8336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Squire J. BookeriD· 2 shared Alexey SilakoviD· 1 shared Bo WangiD· 1 shared Hayley L. KnoxiD· 1 shared Matthew I. Radle· 1 shared Xuekai ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

Squire J. BookerORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedSep 16, 2026

Isolation and In vitro Characterization of BchE, the Cobalamin-Dependent Anaerobic Magnesium Protoporphyrin IX Monomethylester Cyclase Involved in Bacteriochlorophyll Biosynthesis

Nicholas J. York, Xuekai Zhang, Squire J. Booker

This paper isolates and characterizes BchE, a cobalamin-dependent radical SAM enzyme, enabling in vitro studies of its role in bacteriochlorophyll biosynthesis.

DOI 10.1073/pnas.2615158123

experimental assay

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BiochemistryJournal of the American Chemical SocietyPeer-reviewedMay 27, 2026

Structural and Spectroscopic Basis for Catalysis by a Class C Radical S-adenosylmethionine Methylase Involved in Nosiheptide/Nocathiacin Biosynthesis

Bo Wang, Hayley L. Knox, Nicholas J. York…·Squire J. Booker

This paper reports the structural and spectroscopic analysis of a class C radical SAM methylase involved in Nosiheptide biosynthesis, revealing key catalytic residues and radical mechanisms.

1 citation

structural biologyexperimental assay

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