Author

Matthew J. Sears

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Russ P. CarstensiD· 2 shared Hong LiiD· 1 shared Hyun‐Duck Nah· 1 shared Imad SalhabiD· 1 shared Jae Yeon Hwang· 1 shared Juw Won ParkiD· 1 shared Mathieu Quesnel- Vallières· 1 shared Natoya J. Peart· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Russ P. CarstensORCID

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2 papers

Recent·Most cited

The Global Protein-RNA Interaction map of Epithelial Splicing Regulatory Protein 1 defines a post-transcriptional program that is essential for epithelial cell function

Natoya J. Peart, Jae Yeon Hwang, Mathieu Quesnel- Vallières, Matthew J. Sears, Yuequin Yang, Peter Stoilov, Yoseph Barash, Juw Won Park, Russ P. Carstens

The paper identifies ESRP1's genome-wide binding sites and shows its role in splicing regulation and post-transcriptional functions in epithelial cells.

bioRxiv · May 18, 2021 · PreprintMolecular Biology

Cleft lip and cleft palate (CL/P) in Esrp1 KO mice is associated with alterations in Wnt signaling and epithelial-mesenchymal crosstalk

Sungkyoung Lee, Matthew J. Sears, Zijun Zhang, Hong Li, Imad Salhab, Philippe Krebs, Yi Xing, Hyun‐Duck Nah, Trevor Williams, Russ P. Carstens

The paper investigates the role of Esrp1 in cleft lip and palate development in mice, identifying altered Wnt signaling and epithelial-mesenchymal interactions as key factors.

Development · Jan 1, 2020Peer-reviewedDevelopmental Biology