A single Musashi gene allele is sufficient to maintain mouse photoreceptor cells
The paper shows that a single Musashi gene allele is sufficient to maintain photoreceptor function and splicing in mice.
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West Virginia UniversityORCID 0000-0003-1108-7271Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
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The paper shows that a single Musashi gene allele is sufficient to maintain photoreceptor function and splicing in mice.
Natascha Schippel, Jing Wei, Xiaokuang Ma…·Shalini Sharma
This study identifies erythropoietin's role in regulating glycerophospholipid metabolism during human erythropoiesis using single-cell transcriptomics and lipidomics.
Natascha Schippel, Jing Wei, Xiaokuang Ma…·Shalini Sharma
This study identifies an Epo-dependent CFU-E subtype, lateC, characterized by CD71hiCD105hi phenotype and its role in erythropoiesis.
Brooke A. Brothers, Emily R. Sechrest, Li Ma…·Wen‐Tao Deng
This study evaluates AAV gene therapy in BCM mouse models, finding that older mutant mice show reduced treatment efficacy due to decreased transduction and cone degeneration, while specific promoters remain active.
Ali Zahedi Amiri, Choudhary Ahmed, Subha Dahal…·Alan Cochrane
This paper identifies 5342191 as a broad-spectrum antiviral that inhibits HIV-1, adenovirus, coronavirus, and influenza by altering viral RNA accumulation and structural protein expression.
Fatimah Kh. Matalkah, Bohye Jeong, Macie Sheridan…·Peter Stoilov
This study identifies Musashi proteins as essential regulators of protein expression and alternative splicing in photoreceptors, revealing their dual nuclear and cytoplasmic functions.
Natoya J. Peart, Jae Yeon Hwang, Mathieu Quesnel- Vallières…·Russ P. Carstens
The paper identifies ESRP1's genome-wide binding sites and shows its role in splicing regulation and post-transcriptional functions in epithelial cells.
Jesse Sundar, Fatimah Matalkah, Bohye Jeong…·Visvanathan Ramamurthy
This study shows that MSI1 and MSI2 are essential for photoreceptor morphogenesis, contrasting their known role in stem cell maintenance.