Trevor Williams

Notch signaling in the embryonic ectoderm promotes periderm cell fate and represses mineralization of vibrissa hair follicles

This study shows that Notch signaling in the embryonic ectoderm promotes periderm cell fate and prevents mineralization of vibrissa hair follicles, linking it to craniofacial development.

TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway.

The paper shows that TFAP2 paralogs regulate midfacial development via the ALX genetic pathway in mice and zebrafish.

MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses

MusMorph provides standardized mouse morphology data for meta-analyses, including craniofacial and brain structures across developmental stages and genotypes.

AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development.

This study shows that AP-2α and AP-2β regulate chromatin and gene expression in the craniofacial surface ectoderm, affecting facial development and WNT signaling in mice.

Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development

This study shows that Tfap2a and Tfap2b have tissue-specific roles in tooth development, with epithelial expression critical for incisor morphology and mesenchymal expression having little effect.

AP-2γ is Required for Maintenance of Pluripotent Mammary Stem Cells

This study shows that AP-2γ is essential for maintaining pluripotent mammary stem cells and their ability to form mammary gland structures.

Cleft lip and cleft palate (CL/P) in Esrp1 KO mice is associated with alterations in Wnt signaling and epithelial-mesenchymal crosstalk

The paper investigates the role of Esrp1 in cleft lip and palate development in mice, identifying altered Wnt signaling and epithelial-mesenchymal interactions as key factors.